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Anticoagulation

Blood Pressure

Prevent Adverse Drug Reactions

Approximately half of all Americans have genetic defects that affect how they process drugs. Knowledge of your DNA Drug Reaction Profile may help your physician or pharmacist prevent adverse drug reactions.

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Genetic test predicts warfarin sensitivity

A new test was recently released to predict excessive bleeding risks among patients who take warfarin, which is the most frequently prescribed oral anticoagulant used for the prevention and treatment of thromboembolic events. Warfarin is a difficult drug to manage due to its narrow therapeutic range and inconsistent patient response resulting from inter-individual variability.

Genetic information available from the new Warfarin Sensitivity DNA Test, created by Kimball Genetics, will help predict response. The test determines the presence of specific variations in the CYP2C9 andVKORC1 genes that confer sensitivity to warfarin and thus significantly reduce the required maintenance dose. CYP2C9 is involved in warfarin metabolism and VKORC1 influences warfarin's anticoagulation effect through vitamin K. Kimball Genetics expects to offer the Warfarin Sensitivity DNA Test for routine clinical use early in 2007. Read More

Dark chocolate lowers cholesterol

A recent study published in the Journal of the American Heart Association found that it is possible to lower blood pressure levels by eating dark chocolate. One bar of dark chocolate is enough to lower a person’s blood pressure in a natural and enjoyable way... Read More

Stents increase risks for blood clots

New drug-covered stents widely used to prop open clogged arteries are associated with an increased risk of blood clots, heart attacks and death for the majority of patients receiving the devices, an expert panel concluded. Based on the finding... Read More

Folic acid ineffective in reducing heart disease

A new study published in the Journal of the American Medical Association has found that taking a folic acid supplement does not in any way decrease the risk of heart disease or stroke in people with a history of heart problems. The findings of the study... Read More

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Copyright © 2007 QAS, Inc. All rights reserved. The information provided in this Newsletter and on the Hometestmed site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions.